Document Details

Document Type : Thesis 
Document Title :
EMPIRICAL ANALYSIS OF HUMAN BLOOD IN NORMAL AND PATHOLOGIC CONDITIONS USING LASER-INDUCED BREAKDOWN SPECTROSCOPY
التحليل التجريبي لعينات دم الإنسان في الحالة الطبيعية و المرضية بإستخدام تقنية إنهيار الليزر المستحث المطيافي
 
Subject : Faculty of Sciences 
Document Language : Arabic 
Abstract : Empirical Analysis of Human Blood in Normal and Pathologic Conditions using Laser-induced Breakdown Spectroscopy Khadijah Ibrahim Al-malki Abstract This work is considered as a detailed study of the spectroscopic analysis of the laser generated plasma of the normal and pathologic whole dried human blood. The LIBS system has been implemented to generate plasma by applying 1064nm Q-switched Nd: YAG Laser. The normal and pathologic liquid blood samples were collected under the condition of breast cancer, then the liquid blood was dried through Dried Blood Spot (DBS) technique. Dried blood samples were irradiated at the laser energy ranging from 20-90mJ at the best focal position along the laser axis with a single laser pulse. LIBS detected the major metallic elements in the region 190-900nm such as sodium (Na), iron (Fe), calcium (Ca), phosphor (P), magnesium (Mg), lithium (Li), potassium (K) and blood basic elements such as carbon (C) nitrogen (N), hydrogen (H), oxygen (O). To make sure that the created plasma is fully ionized, plasma parameters have been calculated for various energies and focal distances. It’s found that electron temperatures were ranging (8,700 to 11,090K) and electron densities were ranging (1.62x1012– 1.91x1016 cm-3). The reproducibility of blood spectral lines at different laser energies was investigated. The spectral lines were found to be reproduced at different laser energies, focal positions and no. of laser shots. The power spectral density (PSD) function was implemented to study the effect of varying experimental parameters on the DBS spectral lines intensity, as well as, to study the intensity variation of the major blood electrolytes in cancerous subjects. we found that: LIBS was helpful to identify the elements present in human blood, and to study the fluctuation of electrolytes at variase stages of cancer disease and the PSD described successfully the parametric relation between laser energy, laser accumulation and focal dist 
Supervisor : Dr. Rashida Jafer 
Thesis Type : Master Thesis 
Publishing Year : 1439 AH
2018 AD 
Co-Supervisor : Dr. Reem O. Alwafi 
Added Date : Thursday, August 9, 2018 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
خديجة إبراهيم المالكيAl-malki, Khadijah IbrahimResearcherMaster 

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