Document Details

Document Type : Thesis 
Document Title :
Maternal Status of trace Elements in Normal Pregnancy and in Gestational Diabetes Mellitus
حالة العناصر الضئيلة في الحمل الطبيعي والحمل المصاحب بالسكري
 
Subject : Faculty of Sciences > Biochemistry department 
Document Language : Arabic 
Abstract : Adequate nutrition is critical in pregnancy, because both the fetus and an infant are dependent on adequate maternal stores of micronutrients. Iron, copper and zinc are among the essential micronutrients. The aim of this study was to assess iron, copper and zinc status in normal pregnancy and in pregnancies complicated with gestational diabetes mellitus (GDM) compared to non-pregnant women. The associations between serum levels of the studied micronutrient and their related markers with insulin resistance parameters in pregnancy was another target. The study included three groups: non pregnant (n = 44), healthy normal pregnancy (n = 47) and pregnancy complicated with GDM (n = 42). Results revealed significant variations in iron status as indicated by decreased serum iron and elevated TIBC, both in normal pregnancy and in GDM. Serum copper was higher in normal pregnancy and in GDM, while ceruloplasmin was higher in normal pregnancy compared to non-pregnant. Serum zinc showed trend towards decrease in normal pregnancy and no change in GDM compared to non-pregnant group. No significant correlations were obtained between each of iron, copper and zinc status and markers of insulin resistance in pregnancy. It could be concluded that normal pregnancy and GDM are associated with imbalance in iron, copper and zinc status, however, the imbalance in trace elements has no significant role in the decreased insulin sensitivity associated with pregnancy, especially in GDM. 
Supervisor : Prof. Amani Farouk Hussein Noureldeen 
Thesis Type : Master Thesis 
Publishing Year : 1437 AH
2016 AD 
Added Date : Monday, February 29, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ياسمين سراج السلميAL-Solami, Yasmin SeragResearcherMaster 

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