Document Details

Document Type : Thesis 
Document Title :
Effect of cinnamon on plasma glucose concentration and the regulation of 6-phosphofructo-1-kinase activity from the liver and small intestine of streptozotocin induced diabetic rats
تأثير القرفة على تركيز الجلوكوز في البلازما و تنظيم نشاطية 6- فوسفو فركتو-1- كينيز من كبد و أمعاء الجرذان المصابة بداء السكري المستحث بالاستربتوزوتوسين
 
Subject : Biochemistry 
Document Language : Arabic 
Abstract : This research attempts to elucidate the effect of cinnamon, a kind of spices commonly used in Eastern and Middle-eastern countries in their food, on plasma glucose concentration and the regulation of 6- phosphofructo-1-kinase in streptozotocin induced-diabetic rats. The animals were 50 male Wistar rats (180-200 g) divided into five groups: normal controls, untreated diabetics (rats were made diabetic by single I.P. injection of streptozotocin), diabetics rats treated with 0.5g and 1.0g of cinnamon, and the last group of diabetic rats were treated with insulin. This study is concerned with the regulation glucose metabolism in streptozotocin- induced diabetic rats by an estimate of enzyme activity of liver and small intestine. Also, to demonstrate the effect of cinnamon on plasma glucose, cholesterol, triacylglycerol and insulin concentrations. In addition, the present study compares the regulation of PFK-1 of the diabetic rats with another group of diabetic rats treated with cinnamon. The results show a significant decrease (p < 0.0001) in glucose, cholesterol and triacylglycerol concentrations were a significant increase (p < 0.0001) in insulin concentration and the enzyme activity in cinnamon treated groups. In conclusion, cinnamon have a scientific evidence to improve diabetes safely 
Supervisor : Prof. Samir Mohamed Khoja 
Thesis Type : Master Thesis 
Publishing Year : 1427 AH
2006 AD
 
Added Date : Tuesday, June 10, 2008 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سونهام سامي يغمورYaghmour, Ssounaam SamiResearcherMaster 

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